No matter how experienced you may be with using wire frame techniques, it is still a time consuming activity, as is researching a conceptual design as a first step in getting a new project off the ground. While wire frames provide basic frameworks for website pages, pre-made layouts have become an increasingly popular alternative.

Conceptual designs need to be developed before wire framing can commence. Conceptual designs are an integral part of a pre-made layout.
Initial sketches have to be transferred to a grid in to initiate a wire frame process. This step is not required when using pre-made layouts.
Incremental enhancement of a wire frame design takes time. Editing a layout is an extremely rapid process.
With a pre-made layout, you can build a website in a small fraction of the time it would take when using a wire frame approach. You can literally hit the ground running